ASPCA Reports 400% Surge in Pet Kratom Poisoning Cases in 2025 Compared to 2024

Why it matters

A near-400% jump in pet kratom poisoning calls to the ASPCA in one year signals that the substance is increasingly present in homes with animals. Veterinary professionals need practical clinical guidance — and this ASPCA resource provides it.

The big picture

Kratom's growing popularity in the U.S. — available in capsules, gummies, liquids, and chocolates — mirrors a corresponding rise in unintentional pet exposures. As of early 2026, seven states ban kratom outright, while others maintain consumer protection laws. The 7-hydroxymitragynine (7-OH) alkaloid is particularly dangerous for animals, with 13 times the opioid receptor affinity of morphine.

Key findings

• ASPCA Poison Control saw a nearly 400% increase in kratom exposure cases in pets in 2025 versus 2024
• 7-hydroxymitragynine has 46 times the receptor affinity of mitragynine and 13 times the affinity of morphine
• Signs in dogs and cats: lethargy, vocalization, hypersalivation, vomiting; cardiovascular effects also possible
• Doses as low as 0.15 mg/kg can trigger clinical signs in animals
• No antidote exists; treatment is supportive — fluids, benzodiazepines, and naloxone for severe CNS depression
• Signs typically resolve within 24-48 hours in most cases

What they say

"Because of this, it is important to increase awareness of kratom, and its potential adverse effects," states the ASPCA, noting that increased exposures are expected to continue as long as kratom remains present in pets' environments.

Bottom line

Kratom is now a top-tier veterinary toxicology concern — the nearly 400% single-year spike in pet exposures demands that every clinic have a kratom protocol ready.