Case Report Links Kratom Use With Ischemic Colitis

Why it matters

A peer-reviewed case report describes ischemic colitis occurring in the setting of kratom use, adding a rare gastrointestinal complication to the clinical safety literature.

The big picture

Case reports can identify unusual safety signals but cannot establish that kratom caused an event or estimate its frequency. The report is best read alongside broader toxicology and pharmacovigilance data.

Key findings

• The publication reports a novel case of ischemic colitis in a person using kratom.
• The case appeared in Case Reports in Gastroenterology, volume 19, issue 1, pages 590-595.
• The article was published in August 2025 and carries DOI 10.1159/000546558.
• A single case cannot establish incidence or causality.

What they say

The authors describe the report as a novel case and call for attention to possible gastrointestinal complications in kratom users.

Bottom line

**This case expands the list of reported gastrointestinal events but does not prove kratom caused the colitis.**