Kratom Articles and Resources | Kratom Research Institute

October 29, 2024

Exploring the Chemistry of Alkaloids from Malaysian Mitragyna speciosa (Kratom)and the Role of Oxindoles on Human Opioid Receptors

This study explored the chemical composition of kratom leaves from Malaysia and investigated the effects of certain alkaloids found in kratom on opioid receptors. The researchers […]

October 29, 2024

Attitudes towards Kratom use, decriminalization and the development of a community-based Kratom control mechanism in Southern Thailand

The study was conducted in Tambon Namphu, a rural region in southern Thailand where kratom has been used traditionally. Researchers used surveys, interviews, and focus groups […]

October 29, 2024

“Oxidative Metabolism as a Modulator of Kratom’s Biological Actions”

Kratom is a plant from Southeast Asia that some people use to relieve pain and reduce opioid withdrawal symptoms. The article looks at the different chemicals […]

October 29, 2024

Natural Products for the Treatment of Pain: Chemistry and Pharmacology of Salvinorin A, Mitragynine, and Collybolide

This article talks about three natural products that may be able to help with pain. The first one is called salvinorin A, which comes from a […]

October 29, 2024

Front Range Kratom – Warning Letter

On May 18, 2018, the U.S. Food and Drug Administration (FDA) issued a warning letter to Front Range Kratom regarding the sale and distribution of kratom […]

October 29, 2024

Chillin Mix Kratom – Warning Letter

On September 4, 2018, the U.S. Food and Drug Administration (FDA) issued a warning letter to Chillin Mix Kratom, addressing significant safety concerns associated with the […]

October 29, 2024

Kratom Alkaloids as Probes for Opioid Receptor Function: Pharmacological Characterization of Minor Indole and Oxindole Alkaloids from Kratom

This study investigated the pharmacological properties of several minor alkaloids found in the kratom plant, including corynantheidine, mitraciliatine, isopaynantheine, corynoxine, and corynoxine B. The researchers used […]

October 29, 2024

A Novel Mitragynine Analog with Low-Efficacy Mu Opioid Receptor Agonism Displays Antinociception with Attenuated Adverse Effects

Kratom is a plant that has been traditionally used for pain relief and to treat opioid dependence. The main active chemicals in kratom are mitragynine and […]

October 29, 2024

NDI 1264 FDA

The FDA requires manufacturers or distributors of dietary ingredients introduced after October 15, 1994, to submit an NDIN at least 75 days prior to marketing the […]

October 29, 2024

Long-term buprenorphine treatment for kratom use disorder: A case series

This paper looks at 28 people who were addicted to a plant called kratom. Kratom can make people feel good, but it can also be addictive. […]

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