This article talks about three natural products that may be able to help with pain. The first one is called salvinorin A, which comes from a plant called Salvia divinorum. The second one is called mitragynine, which comes from a plant called kratom. The third one is called collybolide, which comes from a type of fungus.
The article explains how these three natural products work on the body’s opioid receptors to reduce pain. It also talks about how scientists are trying to make new versions of these natural products that could be even better at reducing pain without causing as many side effects. The article doesn’t take a strong stance for or against using these natural products, but just tries to give a balanced overview of the science behind them.
The study was done in a lab, not in the real world. It looked at the chemistry and pharmacology of these natural products, but did not test them on animals or humans.
Key takeaways:
- Salvinorin A, mitragynine, and collybolide are natural products that show potential as pain treatments.
- Scientists are trying to modify these natural products to make them more effective and safer.
- The article provides a neutral, scientific overview of the current research on these natural products.
For further reading:
Link: https://pubs.acs.org/doi/10.1021/acs.biochem.0c00629
Full Citation:
Chakraborty, Soumen, and Susruta Majumdar. “Natural Products for the Treatment of Pain: Chemistry and Pharmacology of Salvinorin A, Mitragynine, and Collybolide.” Biochemistry 60.18 (2021): 1381-1400.
