Expanded 2-paragraph summary at 6th grade reading level:

Kratom is a plant that some people use to help with pain, depression, anxiety, and getting off opioid drugs. Kratom has chemicals that act like opioid drugs in the body. This case report is about a man who took a medication called naltrexone for weight loss. Naltrexone blocks the effects of opioid drugs.

The man had been using a lot of kratom every day, but he didn’t tell his doctors. When he took the naltrexone, it caused him to have bad withdrawal symptoms like shaking, sweating, confusion, and hallucinations. He needed to be treated in the intensive care unit to help with his symptoms. This case shows that using kratom can interact with naltrexone and cause serious problems. It’s important for doctors to know if their patients are using kratom or other supplements.

This was a case study done in the real world, not in a lab. It describes what happened to one human patient who was taking both kratom and naltrexone.

Key takeaways:

• Kratom can interact with the medication naltrexone and cause severe withdrawal symptoms
• Patients should tell their doctors about all supplements they are taking, including kratom
• This case highlights the importance of assessing use of herbal supplements like kratom, as they can have serious interactions with medications

For further reading:

https://www.mhc-journal.com/doi/10.9740/mhc.2023.06.155

Full Citation:

Jarka C, Gregoire K. Precipitated withdrawal with kratom use following naltrexone administration. Ment Health Clin [Internet]. 2023;13(3):155-8. DOI: 10.9740/mhc.2023.06.155.